Moreover, some unconventional NMR experiments, such as microliter-scale sample detection and biochemical reaction monitoring, require customized 3D microfluidic sample structures integrated with RF coils 8, 9.
![cst microwave studio mri coil cst microwave studio mri coil](https://ars.els-cdn.com/content/image/1-s2.0-S1090780716302476-fx1.jpg)
Thus, it is imprecise and time consuming to fabricate coils with complex or irregular 3D structures, especially given demands of miniaturization.
#CST MICROWAVE STUDIO MRI COIL MANUAL#
Conventional MR coils are usually fabricated by manual winding and printed circuit board lithography techniques, which generally require labor-intensive manufacturing and 2D fabrication processes 5, 6, 7. As one of the core components of magnetic resonance (MR) systems, radio frequency (RF) coils significantly influence the quality of MR experimental results. With the extensive development of nuclear magnetic resonance (NMR) and magnetic resonance imaging (MRI) techniques, these methods have found wide applications in various fields, such as oncology imaging, biological material detection, substance analysis, and in situ electrochemical reaction monitoring 1, 2, 3, 4. Due to the flexibility and accuracy of 3D printing techniques, we can accurately obtain complicated coil geometries at the micrometer scale, shortening the fabrication timescale and extending the application scenarios. The 3D-printed probeheads are capable of performing both routine and nonconventional MR experiments, including in situ electrochemical analysis, in situ reaction monitoring with continues-flow paramagnetic particles and ions separation, and small-sample MR imaging. We screened different 3D printing materials and optimized the liquid metals by incorporating metal microparticles. The 3D-printed probehead with micrometer precision generally consists of liquid metal coils, customized sample chambers and radio frequency circuit interfaces. Here, we utilized 3D printing and liquid metal filling techniques to fabricate integrative radio frequency probeheads for MR experiments.
![cst microwave studio mri coil cst microwave studio mri coil](https://d3i71xaburhd42.cloudfront.net/5c303218015014901ab4560010eb35ec77f99bbe/10-Figure3-1.png)
However, the fabrication of MR radio frequency probeheads still face difficulties in integration, customization and miniaturization. Magnetic resonance (MR) technology has been widely employed in scientific research, clinical diagnosis and geological survey.